Enoch was created by Caine, Son of Adam some time after he was banished by the Almighty. The First City was a vast wonder of architecture and society, ruled by the Rephaim (vampires) and was a haven for all manner of mundane and supernatural entities. Caine ruled for hundreds of years before slaying all of his direct children (2nd generation vampires) and abandoning it to his vampiric antecedents.
And so you all lived within the Great City until the day the skies turned red and the ground trembled beneath your feat. Grand stone buildings began to topple and the cries of the First City’s citizens rang out in the streets. A deafening thunderclap droned out the other noises, and the heavens opened up, pouring water into the city like rivers. Soon the waters overtook the city, and you struggled to keep above the rapidly rising water before loosing consciousness.